3.2.2 OutcomesafteracutetreatmentBetween-group effect sizes for continuous measures of target disor- der symptoms from pre- to posttreatment were in the medium range (Hedges’ g = 0.56, 95% CI = 0.44–0.69, P < .0001), indicating superior improvement in individuals randomized to CBT over placebo. Effect sizesweresignificantlysmallerforITTsamples(Hedges’ g = 0.40,95%CI = 0.25–0.56, P < .0001) compared to completer samples (Hedges’ g = 0.70,95%CI = 0.54–0.86, P < .0001; QB = 6.85,df = 1, P < .01).The OR for categorical measures of treatment response of CBT compared to placebo condition was 2.97 (95% CI = 2.15–4.10, P < .0001). ORs were again larger for completer samples (OR = 3.69, 95% CI = 2.59– 5.26, P < .0001) than ITT (OR = 2.42, 95% CI = 1.65–3.54, P < .0001), however this difference was not significant (QB = 2.56, df = 1, P = n.s.; seeFigures2and3foraforestplotofeffectsizesandORsofeachindi- vidualstudyincludedintheanalysis).Twenty-six studies reported continuous measures of other anxi- ety symptoms, producing a Hedges’ g of 0.38 (95% CI = 0.25–0.51, P < .0001). Effects of CBT compared to placebo on depression in the26 studies reporting depression outcomes were in the small range (Hedges’ g = 0.31,95%CI = 0.21–0.41, P < .0001).Aminorityofstudies (n = 15)reporteddataonQOL,producingaHedges’ g estimateof0.30 (95%CI = 0.13–0.48, P < .001).